Actor Michael Madsen of Reservoir Dogs received a final text from his child that said, “I love you dad,” and nothing more.
According to his father, 26-year-old Hudson Madsen, a prominent Hollywood actor’s son, shot himself in the head after completing his first tour as a U.S. Army Sergeant stationed in Hawaii.
Star of the Kill Bill franchise Madsen told the LA Times, “I am in shock as my son, whom I just spoke with a few days ago, said he was happy-my last text from him was ‘I love you dad.’”
“I saw no indications of depression. It is so terrible and tragic. He went on, “I’m just trying to make sense of it and comprehend what happened.
Hudson, the oldest child of Madsen and his wife DeAnna Madsen, had Quentin Tarantino as his godfather. The next oldest kids were brothers Luke and Kalvin. Madsen has two more boys, Christian and Max, with his former spouse Jeannine Bisignano.
In 2019, he wed Carlie, who posted encouraging remarks about their love on social media. Carlie’s social media accounts reveal that the couple, unable to conceive naturally, was thinking about doing IVF.
Just one week before he died on January 22, 2022, Carlie posted a selfie of herself wearing a hospital gown to Instagram, captioning it with the news that she had recently had a tumor removed.
She continues in the post, “I just want to give a shout-out to my amazing husband!” Throughout the entire process, he has shown a great deal of patience. I had surgery on one of my breasts yesterday to remove a tumor. Carlie went on, “We spent approximately seven hours at the hospital yesterday. He went to Target and purchased me a card, flowers, cozy pajamas, and my favorite candy while I was in surgery! He has also been tremendous in aiding with my recuperation, and I am incredibly appreciative.
A few weeks later, she posted a sweet photo of herself and Hudson to Twitter with the straightforward message, “I miss you so much.” The circumstances surrounding Hudson’s suicide baffled everyone.
According to Madsen, the 64-year-old father expressed his distress about his suicide by saying, “He had typical life challenges that people have with finances, but he wanted a family.” This is mind-blowing, since he was thinking about his future. I just don’t know what went wrong.
The Once Upon a Time in Hollywood actor Madsen also revealed that, despite his outward contentment, his son—who had served in Afghanistan—was struggling with mental health concerns. The actor claimed that because his son was keeping his difficulties to himself, he stopped getting counseling when he needed it.
Madsen felt “that officers and rank and file were shaming,” so he asked the military to look into it. However, the investigation’s findings are still under wraps.
Known for his work on Quentin Tarantino’s gory comedies, Madsen was arrested in Malibu at the mansion he had just been evicted from, one month after Hudson committed herself. Madsen was charged with trespassing and was given bail.
The actor has a past criminal history; TMZ reports that he was charged with child endangerment in 2012 and with DUI in 2019 following an SUV accident.
When the actor entered his house and saw that his teenage son was using marijuana, the two got into a fight.According to TMZ, Madsen and his young son got into a violent altercation, and when the police arrived, they saw multiple injuries on the boy. According to reports, Madsen looked to be intoxicated when he was taken into custody. Madsen’s name was disclosed, but not that of the son.
After Hudson passed away, the family released a statement in which they said, “We are crushed and overwhelmed with grief and pain at the loss of Hudson.” His memory and light will live on in the hearts of all those who were acquainted with and loved him.
Carlie posts a poignant homage to her spouse, whom she affectionately refers to as “Lump,” on Instagram on January 23, 2023.I have no idea how a year has passed without you. The pain is still exactly the same as it was that day. Every morning when I wake up and every evening before I go to sleep, my thoughts always turn to you. How much I miss you and how much I hurt is beyond words.
“I simply wish you would have spoken with me and told me what was going on that day,” she said. I apologize if you believed that there was no other way to turn things around. I apologize for not seeing the symptoms and for not being able to do more. Regretfully, I let you down. Please know that you are never far from my thoughts or side. Lump, I love you more and I miss you a lot.
Hudson Madsen passed away tragically, leaving behind a husband, best friend, son, and hero. If someone needs to hear it, this is the perfect opportunity to let them know how much you care.
There is always help available, and don’t forget that if you want to talk to someone anonymously, you can call the Suicide Hotline in the United States and Canada at 9-8-8.
We’ve All Waited for It: Scientists Created a Drug That Can Help Regrow Lost Teeth
The tooth fairy is a welcome guest for any child who has lost a tooth. Not only will the fairy leave a small gift under the child’s pillow, but they be assured of a replacement tooth in a few months. Unfortunately, the scenario is quite different for adults grappling with a loss of teeth. Luckily, there may be some hope thanks to a new study performed by scientists at Kyoto University and the University of Fukui.
A dental breakthrough
While the typical adult mouth houses 32 teeth, approximately 1% of the population exhibits variations of them, either possessing more or fewer teeth due to congenital conditions. Researchers have delved into the genetic factors behind cases of excessive teeth, seeking valuable insights into the potential regeneration of teeth in adults. This study is the first to show that monoclonal antibodies can help regrow teeth. It suggests a new way to treat a dental problem that currently requires implants and other artificial solutions.
A bit of science
The research team disclosed that an antibody targeting a specific gene, known as uterine sensitization-associated gene-1 (USAG-1), can induce tooth development in mice affected by tooth agenesis, a congenital condition. The findings were published in the journal, Science Advances.
As per Katsu Takahashi, a senior lecturer at the Kyoto University Graduate School of Medicine and one of the principal contributors to the study, the essential molecules crucial for the development of teeth have already been pinpointed. “The morphogenesis of individual teeth depends on the interactions of several molecules including BMP, or bone morphogenetic protein, and Wnt signaling,” says Takahashi.
On April 13, 2021, the University of Kyoto posted its first pic of newly-grown teeth in mice.
BMP and Wnt are involved in more than just tooth development; they affect the growth of organs and tissues early in the body’s development. Because drugs affecting them directly might have broad side effects, scientists are cautious. To find a potentially safer method, researchers focused on the gene USAG-1, thinking that aiming at factors countering BMP and Wnt specifically in tooth development could be more precise.
“We knew that suppressing USAG-1 benefits tooth growth. What we did not know was whether it would be enough,” added Takahashi.
The first results
Scientists looked at how different monoclonal antibodies affect USAG-1. Monoclonal antibodies are often used to treat things like cancer and arthritis and for making vaccines. Tests with this antibody showed that BMP signaling is crucial for deciding the number of teeth in mice. Also, just one treatment was enough to grow a whole tooth. Further tests confirmed these positive results in ferrets too.
“Ferrets are diphyodont animals with similar dental patterns to humans. Our next plan is to test the antibodies on other animals, such as pigs and dogs,” explained Takahashi.
Fully regrown frontal teeth in ferrets
The next steps
Now, scientists are going to test the drug on healthy adults. If that goes well, the team plans to try it on kids aged 2 to 6 with a rare tooth problem called anodontia, a genetic disorder defined as the absence of all teeth. These kids will get one shot of the drug to see if it makes their teeth grow. If everything works out, the medicine might be approved by 2030.
Takahashi sees the new medicine as an additional choice for individuals who are missing some or all of their teeth.
“The idea of growing new teeth is every dentist’s dream,” Takahashi told the Japanese newspaper, The Mainichi in June this year. “I’ve been working on this since I was a graduate student. I was confident I’d be able to make it happen.”
So hopefully, by the year 2030, humans will get a chance to have their third generation of teeth grown and say goodbye to implants. Until then, make sure to keep your teeth strong and healthy — this article will help you with that.
Preview photo credit KyotoU_News / Twitter
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